QUININE SULPHATE

Use: Night cramps, Malaria

This medicine is mainly indicated for reducing the occurrence of nocturnal leg cramps. It is also used to treat falciparum malaria.

Cautions:

- atrial fibrillation
- heart block/conduction defects
- pregnancy
- G6P deficiency

Contra-indications:

- haemoglobinuria
- myasthenia gravis
- optic neuritis

Side effects:

- cinchonism (tinnitus, headache, nausea, diarrhoea, blurred vision, deafness, vertigo)
- hypersensitivity
- blood disorders
- kidney failure
- hypoglycaemia
- heart arrythmias

Quinine is very toxic in overdose.