TAMOXIFEN

Tamoxifen is an anti-oestrogen used for the treatment of early and advanced breast cancer in pre- and post-menopausal women.

It is also approved by the FDA for the reduction of the incidence of breast cancer in women at high risk of developing the disease.

It has been further approved for the reduction of contralateral (in the opposite breast) breast cancer.

In addition to treating breast cancer, tamoxifen can also be used to treat endometrial cancer.

Tamoxifen competes with oestrogen in the body for oestrogen receptors in breast tissue so that transcription of oestrogen-responsive genes is inhibited.

Tamoxifen