Rasburicase
Rasburicase (brand names: Fasturtec and Elitek) is a recombinant urate oxidase enzyme. It is used for the prevention and treatment of tumour lysis syndrome in patients receiving chemotherapy for hematologic cancers such as leukaemias and lymphomas.
It catalyses the conversion of uric acid to allantoin. Allantoin is much more soluble than uric acid, so renal excretion is more effective
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