Aprepitant

Aprepitant is a chemical compound that belongs to a class of drugs called substance P antagonists (SPA). It mediates its effect by acting on neurokinin 1 receptor.

Aprepitant is marketed by Critical Therapeutics under the brand name Emend™ it is a medication, that is used in the prevention of acute and delayed chemotherapy-induced nausea and vomiting and in the prevention of post-operative nausea and vomiting.

Aprepitant may also be useful in the treatment of cyclic vomiting syndrome but there are few studies to date.

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