Homatropine

Homatropine (Equipin®, Isopto Homatropine®) is an anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It is used in eye drops as a cycloplegic, to temporarily paralyze accommodation, and as a mydriatic, to dilate the pupil.

Homatropine is less potent than atropine and has a shorter duration of action. It is available as the hydrobromide or methylbromide salt

Side effects

  • Blurred vision
  • Sensitivity to light
  • Contraindications

  • Untreated glaucoma
  • Myasthenia gravis
  • Severe heart failure
  • Thyrotoxicosis
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