oestrogen patch

The oestrogen patch is a delivery system for estradiol used as hormone replacement therapy to treat the symptoms of menopause, such as hot flashes and vaginal dryness, and to prevent osteoporosis. Originally marketed as Vivelle® (Novartis), it was discontinued in 2003 and reintroduced in a smaller form as Vivelle-Dot®. Although the oestrogen is given transdermally rather than in the standard oral tablets, the oestrogen patch carries similar risks and benefits as more conventional forms of oestrogen-only hormone replacement therapy. However, it bypasses the liver so avoids the liver effects that occur with use of oral medications.

Administration

Applied to the skin (not breasts) twice weekly. It is generally recommended that it be applied to the lower abdomen or buttocks.

Brand names

  • Esclim
  • Alora
  • Menostar
  • Vivelle-Dot

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