Meropenem

Meropenem is an ultra-broad spectrum injectable antibiotic used to treat a wide variety of infections, including meningitis and pneumonia. It is a beta-lactam and belongs to the subgroup carbapenem.

Meropenem was developed by Sumitomo Pharmaceuticals. It is marketed outside Japan by AstraZeneca with the brand names Merrem® and Meronem®.

Unlike imipenem, it is stable to renal dehydrogenase and can therefore be given without cilastatin. It penetrates into the cerebrospinal fluid. Meropenem also has a reduced potential for causing seizures in comparison with imipenem.

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