Nateglinide
Nateglinide (INN, trade name Starlix®) is a drug for the treatment of type 2 diabetes.
Nateglinide belongs to the meglitinide class of blood glucose-lowering drugs and is sold by Novartis.
Pharmacology
Nateglinide lowers blood glucose by stimulating the release of insulin from the pancreas. It achieves this by closing ATP-dependent potassium channels in the membrane of the beta cells. This depolarizes the beta cells, opening the cells' calcium channels, and the resulting calcium influx induces insulin secretion.
Dosage
Nateglinide is delivered in tablet form.
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