Xylazine

Xylazine is a drug that is used for sedation, anaesthesia, muscle relaxation, and analgesia in animals such as bovine and large mammals (non-human). An analogue of clonidine, it is an agonist at the α2 class of adrenergic receptor. As with other α2 agonists, adverse effects include bradycardia, conduction disturbances, and myocardial depression.

Yohimbine (Yobine) can be used to reverse xylazine effects.

In the laboratory setting, xylazine is often used in combination with ketamine. No formal information in humans is available.

Xylazine is sold by Bayer under the brand name Rompun.

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