Opsoclonus Myoclonus (Kinsbourne syndrome, Myoclonic Encephalopathy of Infants, Dancing Eyes-Dancing Feet Syndrome)

What is Opsoclonus Myoclonus?

Opsoclonus myoclonus is a rare neurological disorder characterised by an unsteady, trembling gait, myoclonus (brief, shock-like muscle spasms), and opsoclonus (irregular, rapid eye movements). Other symptoms may include difficulty speaking, poorly articulated speech, or an inability to speak. A decrease in muscle tone, lethargy, irritability, and malaise (a vague feeling of bodily discomfort) may also be present. Opsoclonus myoclonus may occur in association with tumours or viral infections. It is often seen in children with tumours.

Is there any treatment?

Treatment for opsoclonus myoclonus may include corticosteroids or ACTH (adrenocorticotropic hormone). In cases where there is a tumour present, treatment such as chemotherapy, surgery, or radiation may be required.

What is the prognosis?

The prognosis for opsoclonus myoclonus varies depending on the symptoms and the presence and treatment of tumours. With treatment of the underlying cause of the disorder, there may be an improvement of symptoms. The symptoms sometimes recur without warning. Generally the disorder is not fatal.

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