Travel Guide - Immunobiologics - Missed Doses & Boosters

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Vaccine

Recommendation

Cholera

No longer available in U.S.

Japanese encephalitis

Full duration of protection unknown. Neutralizing antibodies may persist at least 2 years after primary immunisation

Hepatitis A (HAV)

Booster not recommended for adults and children who complete primary series (2 doses)

Hepatitis B (HBV)

Booster doses of vaccine are not recommended for adults and children who completed primary series according to routine schedule.1 Booster is recommended at least 6 months after the start of the accelerated schedule.

Influenza

1 annual dose

Measles, Mumps, Rubella (MMR)

1 dose if measles, mumps, or rubella vaccination history is unreliable and person did not have these illnesses; 2 doses for persons with occupational or other indications

Meningococcal

Quadrivalent A,C, Y, W-135

Full duration of protection is unknown; immunity may persist at least 3 years in adults

Pneumoccocal (polysaccharide)

One-time revaccination 5 years after original dose for persons > 65 years of age or who have immunosuppressive conditions.

Polio (IPV)

For adults who have completed primary series, a single lifetime booster

Rabies

Preexposure vaccine

No serologic testing or boosters recommended for travellers. For persons in higher risk groups, such as rabies laboratory workers, serologic testing and booster doses are recommended. See Table 4–15.

Tetanus/diphtheria (Td)

Booster every 10 years

Typhoid Oral

Booster every 5 years

Typhoid IM

Booster every 2 years

Varicella

Booster not recommended after completion of primary series.

Yellow fever

Booster every 10 years. Note that there are age-related risks for severe adverse reactions.

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Spacing of Immunobiologics

Missed Doses and Boosters