{"id":4337,"date":"2019-07-10T12:55:52","date_gmt":"2019-07-10T12:55:52","guid":{"rendered":"http:\/\/www.medic8.com\/news\/?p=4337"},"modified":"2019-07-10T12:55:54","modified_gmt":"2019-07-10T12:55:54","slug":"new-uk-study-suggests-the-common-cold-virus-could-help-to-destroy-bladder-cancer-cells-4129-8128-6204","status":"publish","type":"post","link":"https:\/\/www.medic8.com\/news\/new-uk-study-suggests-the-common-cold-virus-could-help-to-destroy-bladder-cancer-cells-4129-8128-6204\/","title":{"rendered":"New UK study suggests the common cold virus could help to destroy bladder cancer cells-4129-8128-6204-4206"},"content":{"rendered":"\n

A new UK\nstudy suggests that the virus that causes the common cold can help to destroy\nbladder cancer<\/a> cells. <\/p>\n\n\n\n

Researchers\nfrom the University of Surrey found that a strain of the virus is capable of\ninfecting and destroying cancerous cells within the bladder. In a small trial\nof 15 patients, symptoms disappeared in one patient, and in the other 14, there\nwas evidence to confirm that some cells had been destroyed. <\/p>\n\n\n\n

Having\nanalysed the results of the study, the research team said that the virus could\n\u201crevolutionise treatment\u201d for cases of bladder cancer and also reduce the risk\nof cancerous cells returning after treatment.<\/p>\n\n\n\n

A bladder\ncancer charity hailed the findings as \u201cvery exciting\u201d and called for\nlarger-scale studies to be carried out to determine the potential for new\ntreatment options based on the virus. <\/p>\n\n\n\n

In the UK,\nnon-muscle invasive bladder cancer is currently the 10th<\/sup> most common\ntype of cancer, with around 10,000 new cases diagnosed every year. At present,\nthe treatments tend to be invasive and many cause significant side-effects.\nAfter treatment, patients are also required to undergo frequent testing using expensive\nmonitoring processes. <\/p>\n\n\n\n

During the\ntrial period, 15 patients who had been diagnosed with bladder cancer were given\nCVA21 (coxsackievirus) through a catheter one week before scheduled surgery to\nremove bladder tumours. The team analysed tissue samples after the procedures,\nand found that the virus had targeted and destroyed some of the cancerous\ncells. Once the cells had died, the virus reproduced, infecting other cancerous\ncells, but leaving the healthy cells unharmed. Notably, there were no unpleasant\nside-effects. <\/p>\n\n\n\n

Prof Hardev\nPandha, from the University of Surrey and the Royal Surrey County Hospital,\nexplained that this virus is distinctive because it produces an immune protein\nthat destroys cancerous cells, but it also encourages other immune cells to get\ninvolved and \u201cjoin the party.\u201d Typically, tumours in the bladder are \u2018cold\u2019\nbecause they don\u2019t have immune cells that are capable of destroying cancerous\ncells, but the virus was found to make them \u2018hot\u2019 by\ntriggering an immune response. The virus has previously been trialled on\npatients with skin cancer, but this is the first study to target bladder\ncancer.<\/p>\n\n\n\n

The team is\nnow planning to build on the small trial and use the virus to develop a\ntargeted immunotherapy drug treatment, which is known as a checkpoint\ninhibitor.<\/p>\n","protected":false},"excerpt":{"rendered":"

A new UK study suggests that the virus that causes the common cold can help to destroy bladder cancer cells. Researchers from the University of Surrey found that a strain of the virus is capable of infecting and destroying cancerous cells within the bladder. In a small trial of 15 patients, symptoms disappeared in one […]<\/p>\n","protected":false},"author":888008809,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2145],"tags":[2909,2907,2911,2910,2905,2908,2537,2906,2904],"class_list":["post-4337","post","type-post","status-publish","format-standard","hentry","category-cancer","tag-bladder-cancer","tag-cancerous-cells","tag-prof-hardev-pandha","tag-reduce-the-risk-of-cancerous-cells","tag-researchers-from-the-university-of-surrey","tag-revolutionise-treatment","tag-royal-surrey-county-hospital","tag-strain-of-the-virus","tag-uk-study"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.medic8.com\/news\/wp-json\/wp\/v2\/posts\/4337","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.medic8.com\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.medic8.com\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.medic8.com\/news\/wp-json\/wp\/v2\/users\/888008809"}],"replies":[{"embeddable":true,"href":"https:\/\/www.medic8.com\/news\/wp-json\/wp\/v2\/comments?post=4337"}],"version-history":[{"count":0,"href":"https:\/\/www.medic8.com\/news\/wp-json\/wp\/v2\/posts\/4337\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.medic8.com\/news\/wp-json\/wp\/v2\/media?parent=4337"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.medic8.com\/news\/wp-json\/wp\/v2\/categories?post=4337"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.medic8.com\/news\/wp-json\/wp\/v2\/tags?post=4337"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}