IMIGRAN
Drug: Sumatriptan
Brand name: Imigran
Use: Acute migraine relief
Sumatriptan is a 5HT1 agonist (serotonin agonist) used for the treatment of acute migraine attacks and cluster headache.
Dose:
50 mg orally as soon as possible after the onset of migraine.
Migraine relief should occur within 30 mins of taking Imigran. A second dose should not be taken for the same attack.
Cautions:
- heart disease
- liver impairment
- pregnancy & breast-feeding
- history of seizures
- kidney impairment
Contra-indications:
- ischaemic heart disease
- previous heart attack
- uncontrolled
high blood pressure
- concurrent ergotamine use
Side Effects:
Tingling, heat or tightness, drowsiness, flushing, dizziness, fatigue, visual disturbance, nausea & vomiting.
Interactions:
Ergotamine preparations should be avoided (can cause vasospasm). Antidepressants (MAOIs, SSRIs) and lithium have increased risk of toxicity with Imigran.
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