Desmopressin (Minirin) is a synthetic drug that mimics the action of antidiuretic hormone (ADH). It may be taken nasally, intravenously, or orally.


Desmopressin is used to reduce urine production in central diabetes insipidus patients and to promote the release of von Willebrand factor and factor VIII in patients with coagulation disorders such as type I von Willebrand disease, mild haemophilia A, and thrombocytopaenia. Desmopressin is not effective in the treatment of haemophilia B or severe haemophilia A.

It may also be prescribed to reduce frequent bedwetting episodes in children and adults with enuresis by decreasing nocturnal urine production.

Side effects

- headaches
- facial flushing
- nausea
- stomach upset

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